Compliance with Antipsychotics A Review Study
Amira Hassan Abd El Halim;
Abstract
Medication compliance (synonym; adherence) refers to the degree or extent of conformity to the recommendations about day-to-day treatment by the provider with respect to timing, dosage, and frequency. It may be defined as "the extent to which a patient acts accordance with the prescribed interval and dose of a dosing regimen. Compliance is usually classified as 'good' (75-100% of medication intake), 'fair' (25-75% of intake) or 'poor' (0-25% of intake).
While, medication persistence refers to the act of continuing the treatment for the prescribed duration. It may be defined as "the duration of the time from initiation to discontinuation of therapy".
The terms "therapeutic alliance" and "concordance" reflect that the therapeutic relationship is one of agreement between the doctor and the patient and convey mutual respect for the differing perspectives of both doctor and patient without claiming that the differences between them should be resolved on the grounds of "superior" medical evidence. However, Compliance may have been appropriate when services were driven by paternalism and the practice of medicine was based on patients trusting their doctors. In the 1990s these values and assumptions are changed. The media, consumer groups, policy makers and patients challenge them and look for relationships between doctors and patients that are based more on openness and respect.
Rates of compliance for antipsychotics were found to be lower than those or nonpsychiatric medications. Non-compliance rates vary but figures of up to 90% have been reported with rates for patients prescribed antipsychotics ranging from 24 to 90% and 60 to 92% for a variety of physical disorders.
In an attempt to understand why a high percentage of patients fail to comply regularly with treatment, researchers have investigated a number of factors. With many of these factors it is hard to disentangle cause and effect on the basis of the available evidence, Some are related to the illness-its nature severity and whether it is associated with cognitive deficits. A highly significant factor seems to be the patients subjective feeling of distress or illness. Patients must believe they are ill. Thus asymptomatic patients are at a greater risk for non-compliance than are patients with symptoms. Patients with schizophrenia may not be convinced they are ill. Deluded patients may distrust their doctors.
While, medication persistence refers to the act of continuing the treatment for the prescribed duration. It may be defined as "the duration of the time from initiation to discontinuation of therapy".
The terms "therapeutic alliance" and "concordance" reflect that the therapeutic relationship is one of agreement between the doctor and the patient and convey mutual respect for the differing perspectives of both doctor and patient without claiming that the differences between them should be resolved on the grounds of "superior" medical evidence. However, Compliance may have been appropriate when services were driven by paternalism and the practice of medicine was based on patients trusting their doctors. In the 1990s these values and assumptions are changed. The media, consumer groups, policy makers and patients challenge them and look for relationships between doctors and patients that are based more on openness and respect.
Rates of compliance for antipsychotics were found to be lower than those or nonpsychiatric medications. Non-compliance rates vary but figures of up to 90% have been reported with rates for patients prescribed antipsychotics ranging from 24 to 90% and 60 to 92% for a variety of physical disorders.
In an attempt to understand why a high percentage of patients fail to comply regularly with treatment, researchers have investigated a number of factors. With many of these factors it is hard to disentangle cause and effect on the basis of the available evidence, Some are related to the illness-its nature severity and whether it is associated with cognitive deficits. A highly significant factor seems to be the patients subjective feeling of distress or illness. Patients must believe they are ill. Thus asymptomatic patients are at a greater risk for non-compliance than are patients with symptoms. Patients with schizophrenia may not be convinced they are ill. Deluded patients may distrust their doctors.
Other data
| Title | Compliance with Antipsychotics A Review Study | Other Titles | الطواعيــة علـى مضـــادات الذهـــان دراســة نظريــة | Authors | Amira Hassan Abd El Halim | Issue Date | 2014 |
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