CHEMOTACTIC ACTIVITY OF HELICOBACTER PYLORI AGAINST HUMAN NEUTROPHILS AND MONOCYTES
Fatma Mohamed Abd El-Rahman;
Abstract
This study aimed to detect and isolate Helicobacter pylori from patients suffering of gastroduodenal disorders and to determine its chemotactic activity against human neutrophils.
The laboratory methods used were:
1- Rapid urease test.
2- Direct immunofluorescence antibody technique.
3- Culture using Skirrow's Helicobacter medium as a selective medium.
In this study 25 patients suffered from dyspeptic symptoms were undergo endoscopicy which revealed gastroduodenal disorders (group I) and I 0 patients suffered from the same symptoms but without any endoscopic pathologic findings were selected as a control group (group II).
Groups I and II were divided according to age, sex, residence, socioeconomic status, past history of previous treatment and family history of the same complaint.
I. Rapid urease test showed the least specificity (25%) because it depends on the number of the organism in the sample and it alone can't be considered as a sure positive test.
2. DFA showed high sensitivity (82.3%) as a rapid test but it was less sensitive than culture sensitivity.
The laboratory methods used were:
1- Rapid urease test.
2- Direct immunofluorescence antibody technique.
3- Culture using Skirrow's Helicobacter medium as a selective medium.
In this study 25 patients suffered from dyspeptic symptoms were undergo endoscopicy which revealed gastroduodenal disorders (group I) and I 0 patients suffered from the same symptoms but without any endoscopic pathologic findings were selected as a control group (group II).
Groups I and II were divided according to age, sex, residence, socioeconomic status, past history of previous treatment and family history of the same complaint.
I. Rapid urease test showed the least specificity (25%) because it depends on the number of the organism in the sample and it alone can't be considered as a sure positive test.
2. DFA showed high sensitivity (82.3%) as a rapid test but it was less sensitive than culture sensitivity.
Other data
| Title | CHEMOTACTIC ACTIVITY OF HELICOBACTER PYLORI AGAINST HUMAN NEUTROPHILS AND MONOCYTES | Other Titles | نشاط الهليكوباكتر بيلورى فى جذب كرات الدم البيضاء ( نيتروفيل – المونوسايت ) | Authors | Fatma Mohamed Abd El-Rahman | Issue Date | 1998 |
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