Computer-Based Design and Synthesis of Lapatinib Analogues as Potential Anticancer Agents

Maiada Mohsen Mohamed Sadek;

Abstract


In conclusion, in this study we have introduced four series of 4-anilinoquinazoline derivatives as potent dual EGFR and HER2 inhibitors that have never been reported before.
Compound (IVe) exhibited highly potent anti- EGFR and HER2 inhibitory effect by


Other data

Title Computer-Based Design and Synthesis of Lapatinib Analogues as Potential Anticancer Agents
Other Titles التصميم بواسطة الحاسوب وتشييد مشابهات لدواء لاباتينيب ذات تأثير محتمل مضاد للسرطان “
Authors Maiada Mohsen Mohamed Sadek
Keywords Computer-Based Design and Synthesis of Lapatinib Analogues as Potential Anticancer Agents
Issue Date 2012
Description 
In conclusion, in this study we have introduced four series of 4-anilinoquinazoline derivatives as potent dual EGFR and HER2 inhibitors that have never been reported before.
Compound (IVe) exhibited highly potent anti- EGFR and HER2 inhibitory effect by

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