ROLE OF MATERNAL SERUM FERRITIN IN THE PREDICTION OF LOW NEONATAL BIRTH WEIGHT
Shaimaa Mahmoud Taha Salem;
Abstract
SUMMARY
T
his nested case-control study was conducted in the outpatient clinics in the Obstetrics and Gynecology Department, in Ain Shams University Hospital, Cairo, Egypt from March 2016 to September 2016, aimed to assess the accuracy of maternal serum ferritin level in predicting the development of IUGR in pregnant women.
The study included 64 pregnant women (according to equation and incidence of IUGR) with singleton intrauterine pregnancy, their gestational age ranged between 30 weeks to 32 weeks. Inclusion and exclusion criteria were fulfilled with all patients.
The study was approved by our ethical committee. Full history was taken (Personal, Present, Past, Family, Menstrual and Obstetric history), Physical examination was done (General, Abdominal and Newborn examination), Ultrasound examination for gestational age confirmation through fetal biometry, fetal weight, detection of fetal presentation and exclusion of major congenital malformations.
Measurement of serum ferritin level by venous blood sample, measuring 3 ml that were drawn from the cubital vein at 30-32 weeks of gestation, by using Enzyme-Linked Fluorescent Assay (ELFA).
Results showed that serum ferritin measured at 30-32 weeks of gestation had been significantly higher in women with low birth weight neonates than in women with normal-weighted neonates (p < 0.001). The cutoff value of ferritin level in serum was 18.2 µg/dl with a sensitivity of 59.38%, specificity of 90.62%, Positive Predictive Value (PPV) of 86.4% and Negative Predictive Value (NPV) of 69% and overall accuracy of 76.8%.
In conclusion, level of serum ferritin is a good test for predicting IUGR.
T
his nested case-control study was conducted in the outpatient clinics in the Obstetrics and Gynecology Department, in Ain Shams University Hospital, Cairo, Egypt from March 2016 to September 2016, aimed to assess the accuracy of maternal serum ferritin level in predicting the development of IUGR in pregnant women.
The study included 64 pregnant women (according to equation and incidence of IUGR) with singleton intrauterine pregnancy, their gestational age ranged between 30 weeks to 32 weeks. Inclusion and exclusion criteria were fulfilled with all patients.
The study was approved by our ethical committee. Full history was taken (Personal, Present, Past, Family, Menstrual and Obstetric history), Physical examination was done (General, Abdominal and Newborn examination), Ultrasound examination for gestational age confirmation through fetal biometry, fetal weight, detection of fetal presentation and exclusion of major congenital malformations.
Measurement of serum ferritin level by venous blood sample, measuring 3 ml that were drawn from the cubital vein at 30-32 weeks of gestation, by using Enzyme-Linked Fluorescent Assay (ELFA).
Results showed that serum ferritin measured at 30-32 weeks of gestation had been significantly higher in women with low birth weight neonates than in women with normal-weighted neonates (p < 0.001). The cutoff value of ferritin level in serum was 18.2 µg/dl with a sensitivity of 59.38%, specificity of 90.62%, Positive Predictive Value (PPV) of 86.4% and Negative Predictive Value (NPV) of 69% and overall accuracy of 76.8%.
In conclusion, level of serum ferritin is a good test for predicting IUGR.
Other data
| Title | ROLE OF MATERNAL SERUM FERRITIN IN THE PREDICTION OF LOW NEONATAL BIRTH WEIGHT | Other Titles | دور مستوي الفيريتين في مصل الأم في التنبؤ بانخفاض وزن المواليد عند الولادة | Authors | Shaimaa Mahmoud Taha Salem | Issue Date | 2016 |
Recommend this item
Similar Items from Core Recommender Database
Items in Ain Shams Scholar are protected by copyright, with all rights reserved, unless otherwise indicated.