IMMUNOGLOBULINS PATTERN IN CHILDREN SUFFERING FROM CROUP

Abstract

The aim of this work was put to study the changes in serum and salivary immunoglobulins expected in early days of croup attack in children.

Thirty-four children presented with croup attack constituted the material of this study. The level of their immunoglobulins was compared with the level in nineteen healthy children residing the same districts in Cairo. The relations between the rises of immunoglobulins and different demographic and socioeconomic conditions were assessed. Statistical tests were performed to identify significance.

Results in croup children showed significant rise of serum immunoglobulins A, G and non-significant rise of serum immunoglobulin M because it is a short lasting immunoglobulin. The rise in serum immunoglobulins A, G and M was age dependent with wide individual variations and it became more manifest in older children. Repeated attacks significantly induced higher levels of immunoglobulins A, G and M. Fever rose the concentration of all types of immunoglobulins, insignificant relationship. The salivary immunoglobulin A was not found to be raised with croup.