PREVALENCE OF THIOPURINE METHYLTRANSFERASE GENE POLYMORPHISM IN CHILDREN WITH ACUTE LYMPHOBLASTIC LEUKEMIA

Mai Mostafa Abdel Maksod;

Abstract


P
olymorphisms that reduce the activity of thiopurine S-methyltransferase (TPMT) cause adverse reactions to conventional doses of thiopurines (6-Mercaptopurine, 6-Thioguanine and Azathioprine) routinely used for antileukemic and immunosuppressive treatme


Other data

Title PREVALENCE OF THIOPURINE METHYLTRANSFERASE GENE POLYMORPHISM IN CHILDREN WITH ACUTE LYMPHOBLASTIC LEUKEMIA
Other Titles نسبة انتشار تعدد أشكال جين ثيوبيورين ميثيل ترانسفيريز فى الأطفال المصابين بمرض سرطان الدم الليمفاوى الحاد
Authors Mai Mostafa Abdel Maksod
Keywords PREVALENCE OF THIOPURINE METHYLTRANSFERASE GENE POLYMORPHISM IN CHILDREN WITH ACUTE LYMPHOBLASTIC LEUKEMIA
Issue Date 2010
Description 
P
olymorphisms that reduce the activity of thiopurine S-methyltransferase (TPMT) cause adverse reactions to conventional doses of thiopurines (6-Mercaptopurine, 6-Thioguanine and Azathioprine) routinely used for antileukemic and immunosuppressive treatme

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