A Study Of The Value Of Clinical Assessment, Ultrasonography And "E2" Level Determination In Diagnosis Of Ovulation

Abstract

The ability to accurately predict ovulation, and monitor the different phases of menstrual cycle represents an exciting challenge to those who are concerned with reproductive biology, this is because, it will provide an opportunity to those who are desirous to conceive to optimize their chance by selecting the fertile "' ndow for their sexual relation. On the other hand, this sexual and reproductive awareness will enable couples who don't like to conceive to effectively avoid that critical fertile period, with 'the ultimate result of improvement in life quality of their families without subjecting themselves to the potential hazards of various contraceptives. In addition, the accurate prediction of ovulation represents the corner stone in the success of any assisted reproductive technology (A.R.T) progn1111 as a precise prediction of ovulation, within 24 hours, is needed if artificial insemination is intended and even a more precise prediction, within 0 - 2 hours, is highly required if preovulatory ooc_vtcs are to be harvested for in-vitro fertilization. (I.V.F.) (Adlercreutz, et al., 1980, Stanczyk, ct al., 1980, Collins, et al., 1981, World Health Organization, 1983, Brown, ct

al., 1985 and Cekan, et al, 1 986).

The current state of the art of ovulation prediction and assessment of the fertile period is changing very rapidly and \-\ II continue to evolve over the next several years aiming at a simple and reliable method to achieve that critical goal. Numerous methods based upon understanding or the reproductive physiology, the endocrinological sequences during the ovarian cycle, and the resulting substantial changes in ovarian steroids, oestrogen and progesterone and/or their effects upon the target organs arc currently available. I Iowever, non of these methods seems to be convenient and effective to be considered a standard procedure in reproductive medicine (Moghissi, et al., 1976, Lenton, ct al., I 977,