MOLECULAR LOCAUZATION Of SOME GENES ON CHROMOSOMES OF SCHISTOSOMES
Mahmoud Ahmed El-Banhawy;
Abstract
Schistomiasis is one of most widely spread parasitic diseases affecting man in more than 76 countries in several parts of the world including Egypt and some neighbouring countries.
In recent years, with the aid of modern techniques, such as recombinant DNA technology and computer analysis, studies have been focused on the identification and characterization of defined genes encoding antigens that have potential significance in inducing protective immunity.
An understanding of the mechanisms involved in the expression and regulation of such genes definitely requires a determination of the location oftheir genetic elements within the genome of the corresponding orgamsm.
Chromosome preparations for S. mansoni and S. haematobium were made from schistosome sporocysts isolated from infected B. alexandrina and B. trancatus snails, respectively. The conventional Giemsa karyo types were carried out, and chromosomes were arranged in a series of descending order. Both S. mansoni and S. haematobium has found to have 8 pairs of chromosomes (2n = 16).
C-banding technique was used to differentiate between autosomes and sex chromosomes, in addition to differentiate between male and female cells.
In recent years, with the aid of modern techniques, such as recombinant DNA technology and computer analysis, studies have been focused on the identification and characterization of defined genes encoding antigens that have potential significance in inducing protective immunity.
An understanding of the mechanisms involved in the expression and regulation of such genes definitely requires a determination of the location oftheir genetic elements within the genome of the corresponding orgamsm.
Chromosome preparations for S. mansoni and S. haematobium were made from schistosome sporocysts isolated from infected B. alexandrina and B. trancatus snails, respectively. The conventional Giemsa karyo types were carried out, and chromosomes were arranged in a series of descending order. Both S. mansoni and S. haematobium has found to have 8 pairs of chromosomes (2n = 16).
C-banding technique was used to differentiate between autosomes and sex chromosomes, in addition to differentiate between male and female cells.
Other data
| Title | MOLECULAR LOCAUZATION Of SOME GENES ON CHROMOSOMES OF SCHISTOSOMES | Other Titles | التحديد الجزيئى لبعض الجينات على كروموسومات طفيلى البلهارسيا ( الشيستوسوما ) | Authors | Mahmoud Ahmed El-Banhawy | Issue Date | 1998 |
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