A Study on the Effect of Adhesives on the Physiology and Histology of Guinea Pigs, Blood and Behavior of Occupationally Exposed Workers

Abstract

Organic solvents are one of the prevalent sources of chemical exposures m working populations. Inhalation abuse ore glue sniffing became common among young adolescents. Many reports have focused on addiction and sudden death. Moreover, inhalation of organic solvents can cause injury to several internal organs of human body.

This study aims to detect the effect of orgamc solvents on experimental animals and human occupationally exposed to glue as workers. It is conceivable that the general picture of the effects will vary

depending on the composition of the solvents mixture and the intensity of the exposure should be a function of the extent of effects. Toluene (49%), benzene (15.9%), hexane (24.9%), and acetone (7.9%) are the main components of solvents in shoe glues used and manufactured in Egypt, (Red Golla). Ethyl acetate (31.8%). toluene (47.7%) and hexane (21.2%) were found in special type of glue (White Goll he present study includes four slippers and shoes factories, in Ismailia city (A, B, C and D), where workers are exposed to organic solvents. The medium air concentration of 8-hours work day, 40-hours work

week in work places for organic solvents detected, varies according tn ' 1 • , position of exposure, temperature and conditions present in every factory (ventilation, work place area, and arrangement).