Myocardial Dysfunction In Cirrhotic Patients

Abstract

SUMMARY AND CONCLUSION (91)

SUMMARY AND CONCLUSION

The aim of this work was to study the magnitude of myocardial dysfunction in cirrhotic patients, and the impact of some etiological factors e.g. schistosomiasis or viral hepatitis, and complications e.g. jaundice and ascites on myocardial dysfunction in cirrhotic patients.

Thirty two cirrhotic patients were included in this study as a test group and 26 apparently healthy individuals with a comparable age range as a control group. The test group was further subdivided according to; Severity of liver cirrhosis (Child-pugh classification, into 3 groups A, B & C), etiology of liver cirrhosis (3 subgroups; Pure bilharzia!; viral and mixed), presence or absence of complications (with or without ascites and with or without hyperbilirubinemia) and according to the age of the subjects (into two subgroups with age 45 Y and >45 Y).

All subjects underwent: Full history taking, complete clinical examination and investigations including: liver biochemical tests (S. bilirubin, ALT, AST, S. Albumin, and Prothrombin prolongation), HBsAg, Anti-HCV, IHA for Bilharziasis, Abdominal ultrasonography, X-ray chest, ECG and Echocardiography (including M-mode, 2-D, and Doppler study).

As regards LV dimensions, our study had revealed a highly significant increase of both LVESD and LVEDD in the moderate cirrhosis of Child B group but non-significant changes of these