Effect of soybean on fertility of male and female albino rats

Serag El Din, O.S.; * ; Abd El Fattah, N. ; dr/Nehal abd elfaatah ; Batta, H., Abd El Azim 


Abstract


This study aimed to investigate whether consumption of soybean is useful or harmful on reproductive hormones; ovary; uterus; mammary gland; testis and subsequent fertility. In the former experiment, male and female Wister albino rats were used in the present study. Each sex was randomly divided into 4 groups, control group fed on the basal diet (AIN93 G), three treated groups given 30, 60 and 90 gm cooked soybeans/70 kg human body weight (b.w.) for three months. Female rats showed that soybean significantly decreased free estradiol hormone (E2); progesterone hormone; follicle stimulating hormone (FSH); luteinizing hormone (LH); ovary weight and number of ovarian follicles. On the other hand soybean significantly increased total E2; sex hormone binding proteins (SHBP); uterus weight and caused uterus proliferation and cystic hyperplasia. The mammary gland showed gradual hyperplasia and mammary ducts showed proliferation. In male rats soybean significantly decreased free testosterone hormone; LH and FSH, meanwhile total testosterone hormone, SHBP, testes weight and testes diameter were significantly increased accompanied with spermatogenesis arrest.


Other data

Keywords Soybean; Fertility; Progesterone, Testosterone, Ovary; Testis.
Issue Date 2011
Journal Journal of American Science 2011;7(6):872-883 
Series/Report no. 6;872-883
URI http://research.asu.edu.eg/handle/123456789/1346
ISSN 1545-1003


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