Synthesis, antibacterial, and antiviral evaluation of new heterocycles containing the pyridine moiety
M. S. Salem; Madkour H. M. F.;
Abstract
A facile one-pot four-component reaction was utilized to construct 2-oxo-1,2-dihydropyridine-3-carbonitrile as a scaffold for the synthesis of many fused heterocyclic systems, namely, furopyridine, pyridothiadiazepinthione, and pyridotriazine, as well as non-fused heterocyclic systems such as phthalazin-2(1H)-ylnicotinonitrile, pyridin-2-yl-1H-pyrazole, and pyrazol-1-ylnicotino-nitrile,1-(3-cyanopyridin-2-yl)-1H-pyrazole. The new compounds were evaluated as antimicrobial and antiviral agents. © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Other data
| Title | Synthesis, antibacterial, and antiviral evaluation of new heterocycles containing the pyridine moiety | Authors | M. S. Salem ; Madkour H. M. F. | Issue Date | 1-Oct-2013 | Journal | Archiv der Pharmazie | DOI | 10 766 https://api.elsevier.com/content/abstract/scopus_id/84885677623 346 1521-4184 10.1002/ardp.201300183 |
PubMed ID | 346 | Scopus ID | 2-s2.0-84885677623 |
Recommend this item
Similar Items from Core Recommender Database
Items in Ain Shams Scholar are protected by copyright, with all rights reserved, unless otherwise indicated.