Preparation and application of organophosphorus dimers as antimicrobial agent for bagasse packaging paper.

Abstract

Organophosphorus aniline and p-toluidine dimers were prepared and utilized as antimicrobial coating for bagasse paper sheets. Bagasse paper sheets coated with 1,3-diaryl-2,2,2,4,4,4-hexachlorocyclodiphosph(V)azane (where aryl is aniline or p-toluidine) verify antimicrobial activity against Gram+ve bacteria (Bacillus subtilis, Staphylococcus aureus), Gram-ve bacteria (Pseudomonas aeruginosa, Escherichia coli, Proteus vulgaris), yeasts (Candida albicans, Saccharomyces cerevisiae), and fungi (Aspergillus niger). The attained antimicrobial activity for bagasse paper sheets coated with prepared organophosphorus dimers was attributed to the presence of chlorine and phosphrus atoms, in addition to the lone pair of electrons on nitrogen atoms, in the dimers structure. The best obtainable inhibitory activity of bagasse paper sheets coated with organophosphorus dimers was at 250 mg/mL for aniline dimer, while p-toluidine dimer gave the strongest inhibitory activity at 250-300 mg/mL against most of the tested microorganisms. p-toluidine dimer is much superior to aniline dimer against the investigated microorganisms.