Antioxidant and anti-cancer effect of Egyptian and European pumpkin seed oil

Al-Okbi S., Mohamed D., Kandil E., Ahmed, Emad, Mohammed S.,

Abstract


The aim of the present research was to study the anti-cancer and in-vitro antioxidant activity of Egyptian and European pumpkin seed oil (PSO). The anti-cancer effect of the oils was examined in different human cancer cell lines represented by HepG-2 (liver cancer cells), MCF-7 (breast cancer cells) and Caco-2 (colon cancer cells). Results clarified that Egyptian PSO has significant higher antioxidant activity than the European (105.1 �8.3 and85.5�7.6, p < 0.05; respectively). The two oils could inhibit colon cancer cell line with an IC50value of 0.483mg. Egyptian oil showed higher anti-cancer activity than the European towards liver cancer cell while the Egyptian oil had lower activity towards breast cancer cell compared with the European oil.


Other data

Title Antioxidant and anti-cancer effect of Egyptian and European pumpkin seed oil
Authors Al-Okbi S. ; Mohamed D. ; Kandil E. ; Ahmed, Emad ; Mohammed S. 
Issue Date 1-Sep-2016
Journal Research Journal of Pharmaceutical, Biological and Chemical Sciences 
DOI 5
https://api.elsevier.com/content/abstract/scopus_id/84987720599
574
7
Scopus ID 2-s2.0-84987720599

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