Antioxidant and anti-cancer effect of Egyptian and European pumpkin seed oilAl-Okbi S. ; Mohamed D. ; Kandil E. ; Ahmed, Emad ; Mohammed S.
AbstractThe aim of the present research was to study the anti-cancer and in-vitro antioxidant activity of Egyptian and European pumpkin seed oil (PSO). The anti-cancer effect of the oils was examined in different human cancer cell lines represented by HepG-2 (liver cancer cells), MCF-7 (breast cancer cells) and Caco-2 (colon cancer cells). Results clarified that Egyptian PSO has significant higher antioxidant activity than the European (105.1 ï¿½8.3 and85.5ï¿½7.6, p < 0.05; respectively). The two oils could inhibit colon cancer cell line with an IC50value of 0.483mg. Egyptian oil showed higher anti-cancer activity than the European towards liver cancer cell while the Egyptian oil had lower activity towards breast cancer cell compared with the European oil.
|Issue Date||1-Sep-2016||Journal||Research Journal of Pharmaceutical, Biological and Chemical Sciences||URI||http://research.asu.edu.eg/handle/123456789/168408||DOI||5
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