Functional ingredients and cardiovascular protective effect of pumpkin seed oils

Al-Okbi, S.Y., Mohamed, D.A., Kandil, E., Ahmed, Emad, Mohammed, S.E.,


The objective of the present study was to evaluate the cardiovascular protective effect of Egyptian and European pumpkin seed oil (PSO) in hypercholesterolemic rats. Tocopherols, fatty acids (FAs) and unsaponifiable matter (UNSAP) were assessed in both oils. The results showed that γ-tocopherol was 108 and 273, λ-tocopherol was 3.95 and 0 and d-tocopherol was 0 and 1.58 mg·100 g-1oil of the Egyptian and European, respectively. GLC analysis of FAs revealed the presence of linoleic acid as the major fatty acid in both oils. Feeding a hypercholesterolemic diet produced a significant increase in plasma total cholesterol (T-Ch), triglycerides (TGs), low density lipoprotein cholesterol, T-Ch/HDL-Ch, TGs/HDL-Ch and malondialdehyde and a significant reduction in high density lipoprotein cholesterol (HDL-Ch), vitamin E, and adiponectin. Rats fed on hypercholesterolemic diet with either oil showed a significant improvement in all biochemical parameters. © 2014 CSIC.

Other data

Title Functional ingredients and cardiovascular protective effect of pumpkin seed oils
Authors Al-Okbi, S.Y. ; Mohamed, D.A. ; Kandil, E. ; Ahmed, Emad ; Mohammed, S.E. 
Issue Date 2014
Journal Grasas y Aceites 
Scopus ID 2-s2.0-84894272599

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