Polyhalogenated heterocyclic compoundsKhalil, A. K.
AbstractModel studies show that displacement of fluorine, rather than chlorine, occurs upon reaction of 3,5-dichloro-2,4,6-trifluoropyridine with sodium methoxide and phenoxide. Subsequent hydro-dechlorination can be achieved by reaction with lithium aluminium hydride whereas reaction of sodium in iso-propanol leads to formation of the tri-iso-propoxy pyridine derivative, via nucleophilic substitution of the methoxy group, rather than the dechlorinated products. Macrocycles can be synthesised by reactions of appropriate difunctional oxygen nucleophiles with 3,5-dichloro-2,4,6-trifluoropyridine, one of which was characterised by X-ray crystallography. © 2005 Elsevier B.V. All rights reserved.
|Issue Date||2005||Journal||Journal of Fluorine Chemistry||URI||http://research.asu.edu.eg/handle/123456789/168565||DOI||7
Recommend this item
Items in Ain Shams Scholar are protected by copyright, with all rights reserved, unless otherwise indicated.