Stereoselective Crossed-Aldol Condensation of Hetarylmethyl Ketones with Aromatic Aldehydes in Water : Synthesis of (2E)-3-Aryl-1-hetarylprop-2-en-1-ones

Khalil, A. K. ; Sobahi T. ; Basaif S. ; Hassan M. 


Abstract


Aldol condensation of 2-acetylthiophene, 2-acetylpyrrole and 2-acetylpyridine with different aromatic aldehydes were carried out in water in heterogeneous phases in the presence of cetyltrimethylammonium bromide as cationic surfactant at room temperature. All the reactions occur in a short time with excellent yields of steroselective hetarylpropanones in water as environmental friendly solvent.


Other data

Issue Date 2005
Journal Bulletin of the Korean Chemical Society 
URI http://research.asu.edu.eg/handle/123456789/168576
DOI 11
https://api.elsevier.com/content/abstract/scopus_id/31744446533
1677
26
10.5012/bkcs.2005.26.11.1677


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