Ring transformation and antimicrobial activity of indolyl-substituted 2(3H)-furanones
Abou-Elmagd W.; El-Ziaty, Ahmed; Abdalha A.; Abdalha A.;
Abstract
© 2015 by De Gruyter. A variety of heterocycles of synthetic and biological importance were prepared from 3-(indol-3-yl-methylene)-5-phenyl-2(3H)-furanone (1) and its hydrazide 2. Compounds 1 and 2 were used for the construction of pyridazin-3(4H)-ones 4 and 6; 1,3,4-oxadiazoles 7, 8, and 10; and 1,2,4-triazoles 12, 14, and 15, all bearing a 3-indolyl moiety. The antimicrobial activities of the synthesized compounds were examined against six types of bacteria and two types of fungi.
Other data
| Title | Ring transformation and antimicrobial activity of indolyl-substituted 2(3H)-furanones | Authors | Abou-Elmagd W. ; El-Ziaty, Ahmed ; Abdalha A. ; Abdalha A. | Issue Date | 1-Jun-2015 | Journal | Heterocyclic Communications | DOI | 3 https://api.elsevier.com/content/abstract/scopus_id/84935885402 179 21 10.1515/hc-2015-0008 |
Scopus ID | 2-s2.0-84935885402 |
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