Photodynamic therapeutic effect of indocyanine green entrapped in polymeric nanoparticles and their anti-EGFR-conjugate in skin cancer in CD1 mice

Gamal-Eldeen, Amira M; El-Daly, Sherien M; Borai, Ibrahim H; Wafay, Hanaa A; Abdel-Ghaffar, Abdel-Rahman;

Abstract


Indocyanine green (ICG) is a promising photosensitive agent for photodynamic therapy (PDT) of tumors. Encapsulating ICG dye in polymeric nanoparticles based on PEBBLE technology forming (ICG-PEBBLE) could improve the aqueous stability of the entrapped ICG molecules. The study objective is to investigate the PDT effect of free ICG-PEBBLE and its Anti-EGFR conjugate.


Other data

Title Photodynamic therapeutic effect of indocyanine green entrapped in polymeric nanoparticles and their anti-EGFR-conjugate in skin cancer in CD1 mice
Authors Gamal-Eldeen, Amira M ; El-Daly, Sherien M ; Borai, Ibrahim H ; Wafay, Hanaa A ; Abdel-Ghaffar, Abdel-Rahman 
Issue Date Dec-2013
Publisher ELSEVIER SCIENCE BV
Journal Photodiagnosis and photodynamic therapy 
DOI 446-59
1873-1597
4
459
https://api.elsevier.com/content/abstract/scopus_id/84888069269
10
10.1016/j.pdpdt.2013.03.013
PubMed ID 24284098
Scopus ID 2-s2.0-84888069269
Web of science ID WOS:000328666900017

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