Copper (II)-surfactant complex and its nano analog as potential antitumor agents
Badawi, A.M.; Zakhary, N.I.; Morsy, S.M.I.; Mahmoud Shouckry, Gilane Mohamed Sabry; Mohamed, M.R.; Mousa, A.M.;
Abstract
The in vitro anticancer activity of copper cetyl trimethyl ammonium bromide (Cu-CTAB)-loaded cyclodextrin nanoparticles on Ehrlich ascites carcinoma (EAC), colon cancer cells (HCT 116), liver cancer cells (HepG-2), breast cancer cells (MCF-7), and cervix cancer cells (Hela) was investigated using MTT due assay. Cyclodextrin nanoparticles loaded with Cu-CTAB exerted in vitro anticancer activity against the previous human cancer cell lines comparable to the activity of free non-entrapped in nanoparticles macro-particle Cu-CTAB. The nano analog was synthesized by physical loading using grinding with ball mill. The ratio between Cu-CTAB and cyclodextrin oligosaccharide was 1 Cu-CTAB: 3 cyclodextrin. The particle size of the nano derivative was determined using the transmitted electron microscope (TEM). © Taylor & Francis Group, LLC.
Other data
| Title | Copper (II)-surfactant complex and its nano analog as potential antitumor agents | Authors | Badawi, A.M. ; Zakhary, N.I. ; Morsy, S.M.I. ; Mahmoud Shouckry, Gilane Mohamed Sabry ; Mohamed, M.R. ; Mousa, A.M. | Issue Date | 2009 | Journal | Journal of Dispersion Science and Technology | DOI | 9 1303 1309 http://www.scopus.com/inward/record.url?eid=2-s2.0-70449427624&partnerID=MN8TOARS 30 10.1080/01932690902735439 |
Scopus ID | 2-s2.0-70449427624 |
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