Laboratory Diagnosis of Rifampicin Resistant Pulmonary Tuberculosis through Molecular Techniques
Ahmed Mohamed Ali Mohamed;
Abstract
ABSTRACT
Tuberculosis, caused by Mycobacterium tuberculosis (MTB), is one of the most devastating infectious diseases worldwide, with one-third of the world population being infected.
This study was a laboratory based cross-sectional prospective design. The study was performed at February 2013 to February 2016 in different hospitals in Egypt.
Three hundred and fifty-two patients were recruited during the study, 333 patients were selected to complete in this study.
Patients were classified to two groups according to their age (adult group and children group), adult group was used to evaluate performance of Gene xpert MTB/RIF (GX) in sputum specimens and children group was used to evaluate usefulness of stool GX as diagnostic specimen for pulmonary tuberculosis (PTB). Genotype MTBDRplus was used to detect MTB and susceptibility testing for smears of positive specimens.
Tuberculosis, caused by Mycobacterium tuberculosis (MTB), is one of the most devastating infectious diseases worldwide, with one-third of the world population being infected.
This study was a laboratory based cross-sectional prospective design. The study was performed at February 2013 to February 2016 in different hospitals in Egypt.
Three hundred and fifty-two patients were recruited during the study, 333 patients were selected to complete in this study.
Patients were classified to two groups according to their age (adult group and children group), adult group was used to evaluate performance of Gene xpert MTB/RIF (GX) in sputum specimens and children group was used to evaluate usefulness of stool GX as diagnostic specimen for pulmonary tuberculosis (PTB). Genotype MTBDRplus was used to detect MTB and susceptibility testing for smears of positive specimens.
Other data
| Title | Laboratory Diagnosis of Rifampicin Resistant Pulmonary Tuberculosis through Molecular Techniques | Other Titles | التشخيص المعملي لمرض السل الرئوي المقاوم لرفامبيسين عن طريق التقنيات الجزيئية | Authors | Ahmed Mohamed Ali Mohamed | Issue Date | 2018 |
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