Three-dimensional conformal versus intensity modulated radiation therapy in treatment of nasopharyngeal carcinoma

Abstract

The present study included 54 patients with the diagnosis of nasopharyngeal carcinoma divided into 2 groups, group A was treated using 3D conformal radiotherapy (CRT) whereas group B was treated using Intensity modulated radiation therapy (IMRT). The aim of this study was to evaluate and compare both techniques as regard their efficacy on tumor response, local control, overall survival and progression free and treatment related toxicity between both techniques. Chemotherapy was offered to the two groups in the form of given concurrently with radiation therapy and as adjuvant treatment. The median age in 3DCRT and IMRT 44.9 and 49.9 years respectively. The male to female ratio was 3:1. Staging was corrected according to the AJCC 2002 staging system, there were more T3 and T4 patients in group A than in group B (36.7 % and