Synthesis, characterization and biological activities of some transition metal complexes with novel Schiff bases

Abstract

Schiff bases have a pivotal role in the development of coordination chemistry of main group elements, transition metals and lanthanides and gained importance because of their physiological and pharmacological activities. Owing to the easy tunability of their stereo-electronic structures, Schiff bases are privileged ligands because they easily synthesized and form stable complexes with most of the transition metal ions and stabilized them in various oxidation states. Metal complexes of sulfur and nitrogen containing ligands such as Schiff bases has been the subject of current and growing interest in the field of coordination chemistry, because it has been shown that many of these complexes possess wide applications in various areas of science such as anticancer, antitumor, antifungal, antibacterial and antioxidant activities. Di- and polynuclear metal complexes of transition metals (including many Schiff base complexes) have been continuing interest because of their roles as biological models, as catalysts for organic reactions.