Surgical Management of Parkinson’s Disease
Mohammad Eid Mohammad;
Abstract
Abstract
Background: Parkinson’s disease is the second most common neurological disorder. Surgical therapy for Parkinson’s disease has a long history beginning in the 1930s. recently, with better understanding of the pathophysiological basis underlying the development of PD in addition to the advances in imaging technology and electrophysiological techniques used for localization of brain structures have improved the ability to accurately identify and targeting deep brain nucleus as a management to Parkinson’s disease.
Objectives: Evaluation of outcome of treatment of Parkinson disease using different surgical modalities (ablation or stimulation procedures) and different targets mainly (VIM, GPI, or STN).
Methods: Twenty five patients underwent surgeries to control the symptoms of Parkinson’s Disease. Unilateral pallidotomy was done in eleven patients, unilateral thalamotomy was done in ten patients and bilateral DBS was done in four patients. The paents were evaluated preoperatively and 1 month, 6 and 18 months post-operatively both clinically and using the Unified Parkinson’s Disease Rating Scale (UPDRS).
Background: Parkinson’s disease is the second most common neurological disorder. Surgical therapy for Parkinson’s disease has a long history beginning in the 1930s. recently, with better understanding of the pathophysiological basis underlying the development of PD in addition to the advances in imaging technology and electrophysiological techniques used for localization of brain structures have improved the ability to accurately identify and targeting deep brain nucleus as a management to Parkinson’s disease.
Objectives: Evaluation of outcome of treatment of Parkinson disease using different surgical modalities (ablation or stimulation procedures) and different targets mainly (VIM, GPI, or STN).
Methods: Twenty five patients underwent surgeries to control the symptoms of Parkinson’s Disease. Unilateral pallidotomy was done in eleven patients, unilateral thalamotomy was done in ten patients and bilateral DBS was done in four patients. The paents were evaluated preoperatively and 1 month, 6 and 18 months post-operatively both clinically and using the Unified Parkinson’s Disease Rating Scale (UPDRS).
Other data
| Title | Surgical Management of Parkinson’s Disease | Other Titles | العلاج الجراحي لمرضى الشلل الرعاش | Authors | Mohammad Eid Mohammad | Issue Date | 2018 |
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