CLINICAL AND BRAIN IMAGING ASSESSMENT OF SOME HIGH RISL.NEWBORNS
Nafisa Hassan Refat Abd ElAziz;
Abstract
Our study was conducted on 81 high risk newborns (35 preterms,
46 fullterms) in addition to 20 healthy newborns (9 preterms, II fullterms) as a control group matched with study group regarding gestational age and sex. They were recruited from neonatal ICU of Assiut University hospital.
Full maternal history was taken for all cases and controls including maternal age, maternal parity, maternal preeclampsia, parental consanguinity, mode and place of delivery. Full clinical examination was done for all cases and controls including gestational age assessment, anthropometric measurements (weight, length and head circumference) vital signs (heart rate, systolic blood pressure, respiratory rate and tempreture) and some clinical signs (birth injury, raised fontanel, neurological signs, apnea, respiratory distress score and oxygen therapy). Laboratory investigations were done to all cases and controls including biochemical (blood sugar, serum calciwn, serum sodiwn, serum potassium, total and direct bilirubin, blood urea and serwn creatinine), complete blood picture (beamog!obin, white blood cells count and platletes) and blood gas analysis (Ph, PC02, P. 0 2 saturation). Radiological investigations were done for all cases and controls including transcranial sonar, brain CT, and transcranial Doppler studies of internal carotid artery, middle cerebral artery and anterior cerebral artery for mean velocity, pulsatility index and resistive index.
Significantly higher percentage of primiparity was observed in mothers of our fullterms with HIE and meningitis. Significantly higher frequency of positive parental consanguinity was observed in our fullterms with CNS congenital anomalies. Frequency of non - hospital
46 fullterms) in addition to 20 healthy newborns (9 preterms, II fullterms) as a control group matched with study group regarding gestational age and sex. They were recruited from neonatal ICU of Assiut University hospital.
Full maternal history was taken for all cases and controls including maternal age, maternal parity, maternal preeclampsia, parental consanguinity, mode and place of delivery. Full clinical examination was done for all cases and controls including gestational age assessment, anthropometric measurements (weight, length and head circumference) vital signs (heart rate, systolic blood pressure, respiratory rate and tempreture) and some clinical signs (birth injury, raised fontanel, neurological signs, apnea, respiratory distress score and oxygen therapy). Laboratory investigations were done to all cases and controls including biochemical (blood sugar, serum calciwn, serum sodiwn, serum potassium, total and direct bilirubin, blood urea and serwn creatinine), complete blood picture (beamog!obin, white blood cells count and platletes) and blood gas analysis (Ph, PC02, P. 0 2 saturation). Radiological investigations were done for all cases and controls including transcranial sonar, brain CT, and transcranial Doppler studies of internal carotid artery, middle cerebral artery and anterior cerebral artery for mean velocity, pulsatility index and resistive index.
Significantly higher percentage of primiparity was observed in mothers of our fullterms with HIE and meningitis. Significantly higher frequency of positive parental consanguinity was observed in our fullterms with CNS congenital anomalies. Frequency of non - hospital
Other data
| Title | CLINICAL AND BRAIN IMAGING ASSESSMENT OF SOME HIGH RISL.NEWBORNS | Other Titles | تقييم اكلينيكى وبوسائل التصوير المختلفة للمخ فى بعض الاطفال حديثى الولادة المعرضين للخطورة الشديدة | Authors | Nafisa Hassan Refat Abd ElAziz | Issue Date | 2004 |
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