Image Quality and Attenuation Values of Multidetector CT Coronary Angiography Using High Iodine-Concentration Contrast Material: A Comparison of the use of Iopromide 300 and Iopromide 370

Abstract

n the evaluation of patients with suspected coronary artery disease (CAD), the role of non-invasive imaging has increased exponentially over the past decades, particularly in patients with an intermediate likelihood of CAD. Multi-detector computed tomography (MDCT) has emerged as a powerful tool for accurate non-invasive assessment of CAD whenever ―appropriate‖. It has a high sensitivity and specificity for diagnosis and risk assessment of CAD if used appropriately and with proper patient selection. Arterial enhancement is generally determined by the number of iodine molecules administered. The rate of iodine administration can be increased either by increasing the injection flow rate or by increasing the iodine concentration of the contrast agent. However, the degree of arterial enhancement following the intravenous injection of the same amount and type of contrast material is highly variable among individuals for many factors. Each of the contrast medium concentrations has its advantages and disadvantages. Moderate concentration contrast media are currently used for most types of CT examinations, which results in a logistic advantage if the contrast medium (concentration) does not need to be changed for cardiac CTA. However, the use of lower concentration contrast media for