Effect of Thrombolytic Therapy On The Evolution Of Significant Mitral Regurgitation In Patients With Inferior Myocardial Infarction
MOHAMED SALAH ELDIN AHMED;
Abstract
Mitral regurgitation IS a serious and relatively common complication following acute MI. It is more common in inferior or posterior MI.
Restoration of the mitral valve competence is associated with improved hemodynamics & increased survival in patients with
isclH;mic such as
MR. While this is proved by revascularization procedures
PTCA or CABO, the possible protective role of
thrombolytic
established.
therapy on mitral valve competence has not been well
We hypothesized that thrombolytic therapy will reduce the incidence and severity of MR after inferior MI.
To prove this, we studied 50 patients, with a first inferior Ml, all received the conventional treatment for AMI, and the first 25 patients received additionally streptokinase as thrombolytic therapy (the treatment group). While the remaining 25 patients formed (the control group) did not due to either late anival or contraindications to thrombolysis. Echo-Doppler study was done I hour after initiation of therapy & I month after AMI aumng to study MR & LV functions.
Restoration of the mitral valve competence is associated with improved hemodynamics & increased survival in patients with
isclH;mic such as
MR. While this is proved by revascularization procedures
PTCA or CABO, the possible protective role of
thrombolytic
established.
therapy on mitral valve competence has not been well
We hypothesized that thrombolytic therapy will reduce the incidence and severity of MR after inferior MI.
To prove this, we studied 50 patients, with a first inferior Ml, all received the conventional treatment for AMI, and the first 25 patients received additionally streptokinase as thrombolytic therapy (the treatment group). While the remaining 25 patients formed (the control group) did not due to either late anival or contraindications to thrombolysis. Echo-Doppler study was done I hour after initiation of therapy & I month after AMI aumng to study MR & LV functions.
Other data
| Title | Effect of Thrombolytic Therapy On The Evolution Of Significant Mitral Regurgitation In Patients With Inferior Myocardial Infarction | Other Titles | تاثير عقار مذيب الجلطه على حدوث ارتجاع الصمام الميترالى فى مرضى احتشاء عضله القلب السفليه | Authors | MOHAMED SALAH ELDIN AHMED | Issue Date | 2000 |
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