Biofilm Forming Ability and Antimicrobial Susceptibility of Streptococcus Agalactiae Isolated from Pregnant Females

Abstract

Abstract Biofilm formation by Streptococcus agalactiae has a vital role in host-colonization. Pregnant female colonization increases the risk of premature rupture of membrane, stillbirth and low birth weight babies, as well as early onset neonatal disease. Resistance of Group B Streptococci (GBS) to antimicrobials is rising, biofilm formation of GBS, not only facilitate its persistence but also add to the resistance to antimicrobials. This study aimed to detect the antimicrobial susceptibility and biofilm forming ability of GBS colonizing the genital tract of high risk and low risk pregnant females. Vaginal swab from 100 pregnant females between 35-37 weeks of pregnancy was cultured on Blood agar and on Chromatic STREPTO B media. Disk-diffusion test for isolated GBS was done for penicillin, vancomycin, erythromycin & clindamycin.