Angiotensin-Converting Enzyme Insertion/Deletion Gene Polymorphism (ACE I/D) in Egyptian Healthy Children and Adolescents
Mennatullah Ibrahim Abd Elhamid;
Abstract
he rennin-angiotensin system (RAS) is a complex multifaceted endocrine and paracrine system that mediates extracellular fluid and blood pressure homeostasis as well as a large variety of local physiological process at tissue level.
A widely prevalent insertion/ deletion (I/D) polymorphism in the ACE gene, characterized by the presence or absence of a 287-base-pair fragment, accounts for half of the variance in circulating levels of ACE, with II, ID and DD genotypes associated with lower, intermediate and higher plasma levels of the enzyme, respectively.
A widely prevalent insertion/ deletion (I/D) polymorphism in the ACE gene, characterized by the presence or absence of a 287-base-pair fragment, accounts for half of the variance in circulating levels of ACE, with II, ID and DD genotypes associated with lower, intermediate and higher plasma levels of the enzyme, respectively.
Other data
| Title | Angiotensin-Converting Enzyme Insertion/Deletion Gene Polymorphism (ACE I/D) in Egyptian Healthy Children and Adolescents | Other Titles | تعدد أشكال جين الأنزيم المحول للأنجيوتنسين فى الأطفال والمراهقين المصريين الأصحاء | Authors | Mennatullah Ibrahim Abd Elhamid | Issue Date | 2018 |
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