POLYMER FREE DRUG-ELUTING STENTS VERSUS DURABLE POLYMER DRUG-ELUTING STENTS IN ELECTIVE PERCUTANEOUS CORONARY INTERVENTIONS IN PATIENTS WITH STABLE CORONARY ARTERY DISEASE PATIENTS: A SINGLE CENTER PROSPECTIVE COMPARATIVE STUDY

Abstract

he theory of the presence polymeric coating in drugeluting stents was highly debated in the literature regarding its role in provoking delayed arterial healing and delayed hypersensitivity response which may be responsible for late lumen loss (LLL), target lesion revascularization (TLR) and major adverse cardiac events (MACE). Most of the clinical trials in literature focused on comparing the clinical outcome between permanent polymer and polymer free drug-eluting stents, but there is little data in about the inflammatory effect of the permanent polymer versus polymer free drug eluting stents in association with the clinical outcome. The aim of this is study was to compare the inflammatory response of polymer free versus permanent polymer drugeluting stents (DES) in patients with stable coronary artery disease undergoing elective percutaneous coronary intervention, and the effect of this inflammatory response on the 6 month clinical outcomes & major adverse cardiac events. This randomized prospective randomized study was conducted on 100 patients with stable coronary artery disease (SCAD) planned for elective percutaneous coronary interventions who presented to the cardiology department in