The Effect of Misoprostol on Intra-operative Blood Loss during Myomectomy Operation: Randomized Controlled Trial

Abstract

yomectomy is the best option for women who have not completed child bearing or otherwise wish to retain their uterus. Many techniques used to reduce blood loss during myomectomy including preoperative Correction of anemia, preoperative GnRH agonists, intraoperative tourniquets and clamps, intramyometrial vasopressin and other vasoconstrictors and uterotonics (Misoprostol, Oxytocin, etc.). Misoprostol is a stable, synthetic form of prostaglandin E1 analogue which acts to¬¬¬¬¬¬¬ reduce blood loss by increasing myometrium contractions together with the direct vasoconstrictive impact on uterine arteries.