Pre-micro RNA polymorphism detection in small versus large vessel disease in stroke patients
Alaa Amgad Alzahaby;
Abstract
ABSTRACT
Background: Cerebrovascular accidents are the second leading cause of death and the third leading cause of disability worldwide. The methods currently available for diagnosis and prognosis of cerebral ischaemia still require further improvements. Micro-RNAs (small non-coding RNAs) have been recently reported as useful biomarkers in diseases such as cancer and diabetes. Further research concerned with microRNA (miRNA) profiling from peripheral blood to detect and identify characteristic patterns in ischaemic stroke is crucial.
Aim of the Work: This study aims to investigate the association between three potentially functional polymorphisms in pre-miRNAs and stroke subtypes (small vessel disease and large vessel disease) in a sample of Egyptian stroke patients.
Background: Cerebrovascular accidents are the second leading cause of death and the third leading cause of disability worldwide. The methods currently available for diagnosis and prognosis of cerebral ischaemia still require further improvements. Micro-RNAs (small non-coding RNAs) have been recently reported as useful biomarkers in diseases such as cancer and diabetes. Further research concerned with microRNA (miRNA) profiling from peripheral blood to detect and identify characteristic patterns in ischaemic stroke is crucial.
Aim of the Work: This study aims to investigate the association between three potentially functional polymorphisms in pre-miRNAs and stroke subtypes (small vessel disease and large vessel disease) in a sample of Egyptian stroke patients.
Other data
| Title | Pre-micro RNA polymorphism detection in small versus large vessel disease in stroke patients | Other Titles | مقارنة بين الاختلافات الجينية فى مرضى السكتة الدماغية نتيجة اعتلال الأوعية المخية الصغيرة و الكبيرة | Authors | Alaa Amgad Alzahaby | Issue Date | 2018 |
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