Non-invasive Hemodynamic Monitoring in Prediction of the Outcome and Prognosis in Sepsis

Abstract

Patients with signs and symptoms of severe sepsis and septic shock present a clinical challenge and require early and aggressive resuscitation. A recent consensus report defines sepsis as “life-threatening organ dysfunction caused by a dysregulated host response to infection”. Septic shock is defined as a “subset of sepsis in which particularly profound circulatory, cellular, and metabolic abnormalities are associated with a greater risk of mortality than with sepsis alone”. Clinical indicators of sepsis are defined by a two steps screening method. The first step should be identification of infection. The second step should be identification of organ dysfunction by the same organ dysfunction criteria, including lactate level greater than 2 mmol/L or qSOFA score more than two over three criteria.