Efficacy of pregabalin as adjuvant analgesia to diclofenac sodium in laparotomies for benign gynaecological diseases: A Randomized Controlled Trial

Abstract

ABSTRACT Background: abdominal surgeries are considered one of the most painful among all types of surgeries. About 70% of patients who had done abdominal surgeries suffered from severe pain in the postoperative period especially the gynaecological one. This pain and fatigue are the two key causes of prolonged convalescence following abdominal surgery. In order to relieve these pain and fatigue, a current predominant approach of multimodal postoperative analgesia is used, mostly based on a combination of opioids, non-steroidal anti-inflammatory drugs (NSAIDs), paracetamol, and perioperative administration of local anesthetics. Each of these different approaches has its own set of complications.