Comparison between Single Fraction versus Multiple Fraction Radiotherapy in Terms of Pain Control and Prevention of Skeletal related Events in Patients with Bone Metastasis Candidates for Radiotherapy
Sara Abd El Mohdy Ibrahim;
Abstract
ABSTRACT
Background: Metastasis are the most common type of malignant tumor which involve bone, according to OSCER (Oncology Services Comprehensive Electronic Record) among 382,733 study patients, breast cancer (36 %), lunge cancer (60%), and colorectal cancer (12%) were the most common, incidence of bone metastasis was 2.9% at 30 days, 4.9% at 1 year, 5.6% at 2 years, 6.9% at 5 years, 8.4 % at 10 years. Incidence varied by tumor type with prostate cancer patients were at highest risk (18%-29%) followed by lunge, renal and breast cancer.
Aim of the Work: This study aim to prove the equivalency and the efficacy of single fraction radiotherapy (800cGY) and multiple fraction radiotherapy (10 fractions, 300 cGY / fraction, 1 fraction / day, 5 days per week over 2 weeks to a total of 3000cGy) in terms of pain relief and prevention of skeletal related events.
Background: Metastasis are the most common type of malignant tumor which involve bone, according to OSCER (Oncology Services Comprehensive Electronic Record) among 382,733 study patients, breast cancer (36 %), lunge cancer (60%), and colorectal cancer (12%) were the most common, incidence of bone metastasis was 2.9% at 30 days, 4.9% at 1 year, 5.6% at 2 years, 6.9% at 5 years, 8.4 % at 10 years. Incidence varied by tumor type with prostate cancer patients were at highest risk (18%-29%) followed by lunge, renal and breast cancer.
Aim of the Work: This study aim to prove the equivalency and the efficacy of single fraction radiotherapy (800cGY) and multiple fraction radiotherapy (10 fractions, 300 cGY / fraction, 1 fraction / day, 5 days per week over 2 weeks to a total of 3000cGy) in terms of pain relief and prevention of skeletal related events.
Other data
| Title | Comparison between Single Fraction versus Multiple Fraction Radiotherapy in Terms of Pain Control and Prevention of Skeletal related Events in Patients with Bone Metastasis Candidates for Radiotherapy | Other Titles | دراسه مستقبليه للمقارنه ما بين الاشعاع المكثف والاشعاع المتعدد من حيث تقليل الألم و منع الحوادث الهيكليه في مرضي ثانويات العظام | Authors | Sara Abd El Mohdy Ibrahim | Issue Date | 2018 |
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