Protein Aversion in Children with Epilepsy on Valproate Therapy

Abstract

lthough there weren’t much data about the occurrence of protein aversion in patients on valproate therapy, yet, observing many patients on valproate whose parents complaining of protein aversion provoked us to conduct this study. The Aim of this work was to study the relationship between protein aversion and valproate therapy in epileptic children and whether it is related to ammonia level or not. Our cross sectional study was conducted on two groups (patient group and control group). Each group included 45 children from 2 to 16 years old fulfilling the inclusion citeria. They were recruited during the period of September 2016 to December 2017. The patient group included 23 males and 22 females recruited from Pediatric Neurology Clinic, Children's Hospital, Faculty of Medicine, Ain Shams University. They were further subdivided into two subgroups A & B (subgroup A included patients with protein aversion, subgroup B included patients without protein aversion).