RECENT STUDIES ON ACUTE FOWL CHOLERA INFECTION

Abstract

Fowl cholera is a contagious bacterial disease caused by P. multocida and affects domestic and wild birds causing devastating economic hazards of poultry industry. The present study aimed to investigate the incidence of P. multocida in chickens layers and breeders flocks from 4 Egyptian governorates located in El-Delta by isolation and identification of P. multocida, then trial for preparation of locally inactivated vaccine from the predominant P. multocida isolated strains and determination of its efficacy. Moreover, detection of the in-vitro antibiogram of the predominant isolate of strains was done. A total of 330 freshly dead birds (234 layers and 96 breeders) were collected from 55 farms belonging to El-Sharqia (22), El-Gharbia (14), El-Qalubia (11) and El-Minofia (8) governorates, Egypt. All the examined bird had history of septicaemia (congestion and cyanosis of comb and wattles), nasal and ocular discharge, conjunctivitis, greenish diarrhea, and increased mortality (5-10%), with lesions of severe septicaemia, spleen congestion, liver necrosis,