STUDY OF THE ACTIVE CONSTITUENTS AND THE BIOLOGICAL EFFECTS OF TRIUMFETTA FLAVESCENS HOCHST
Mai Mohmmed Ahmed Abdallah Abo Attia;
Abstract
Abstract
The current investigation includes a phytochemical and a biological evaluation of the flowering aerial parts of Triumfetta flavescens Hochst. Application of various chromatographic and spectral techniques resulted in the isolation and identification of five chemical compounds of the plant.These compounds are identified as quercetin 7-O-rhamnoside, kaempferol 3-O-(p-coumaroylglucoside)(tiliroside), 6,4-dihydroxy-3-propen chalcone, I3,II8-biapigenin, β sitosterol and stigmasterol. Amino acids, phenolics, free and combined Sugars, fatty acids and unsaponifiable matters were determined qualitatively and quantitatively. The LD50 of the plant 70% ethanol extract was determined and revealed that the plant is safe at dose up to 7000 mg/kg body weight.The 70% ethanol extract of the flowering aerial parts of the plant showed significant diuretic activity as well as a good in vitro antimicrobial and cytotoxic effects of plant.
The current investigation includes a phytochemical and a biological evaluation of the flowering aerial parts of Triumfetta flavescens Hochst. Application of various chromatographic and spectral techniques resulted in the isolation and identification of five chemical compounds of the plant.These compounds are identified as quercetin 7-O-rhamnoside, kaempferol 3-O-(p-coumaroylglucoside)(tiliroside), 6,4-dihydroxy-3-propen chalcone, I3,II8-biapigenin, β sitosterol and stigmasterol. Amino acids, phenolics, free and combined Sugars, fatty acids and unsaponifiable matters were determined qualitatively and quantitatively. The LD50 of the plant 70% ethanol extract was determined and revealed that the plant is safe at dose up to 7000 mg/kg body weight.The 70% ethanol extract of the flowering aerial parts of the plant showed significant diuretic activity as well as a good in vitro antimicrobial and cytotoxic effects of plant.
Other data
| Title | STUDY OF THE ACTIVE CONSTITUENTS AND THE BIOLOGICAL EFFECTS OF TRIUMFETTA FLAVESCENS HOCHST | Other Titles | دراسة على المكونات الفعالة والتأثير البيولوجي لنبات تكاييت جبل (تريومفيتا فلافيسنس) | Authors | Mai Mohmmed Ahmed Abdallah Abo Attia | Issue Date | 2018 |
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