Hyperglycemia is a Predictive of Poor Outcome in Stroke Patients: A Prospective Randomized Trial

Abstract

SUMMARY S troke is the third most common cause of disability and second most common cause of death worldwide. Hyperglycemia is common during acute ischemic stroke. Several studies have shown admission blood glucose is elevated in >40% of patients with acute ischemic stroke, most commonly among patients with a history of diabetes mellitus. Stroke related hyperglycemia is a stress response with activation of the hypothalamo-hypophyseal-adrenal axis, which leads to an increase in cortisol and catecholamines. The aim of this work was to evaluate the prognostic significance of stress hyperglycemia in acute ischemic stroke.