Molecular Design and Synthesis of Heterocyclic Compounds with Potential Biological Activity
Mai Ibrahim Ibrahim Shahin;
Abstract
No new and effective treatments have been approved for the treatment of esophageal squamous cell carcinoma (ESCC) in the past decade. Cisplatin and 5-fluoruracil are the most commonly used drugs for this disease. In order to develop a new class of drugs effective in our ESCC phenotypic screens, we began a systematic approach to generate novel compounds based on the 2-oxo-1,2-dihydroquinoline-4-carboxamide fragment.
Other data
| Title | Molecular Design and Synthesis of Heterocyclic Compounds with Potential Biological Activity | Other Titles | "التصميم الجزيئى و تشييد مركبات غير متجانسة الحلقة ذات فاعلية بيولوجية محتملة" | Authors | Mai Ibrahim Ibrahim Shahin | Issue Date | 2018 |
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