“Protective effect of marine animal extracts on carbon tetrachloride induced hepatotoxicity in mice
Eman Abdel Aal Abdel Aati Khalil;
Abstract
The present work on male adult albino mice investigated the hepatoprotective role of Chiton extract and Puffer fish extract against hepatotoxicity induced by carbon tetrachloride.
In this work the following studies were used:
• Chemical studies for Chiton extract.
• Biochemical studies for Chiton and Puffer fish extract.
• Histological and Histochemical studies for Chiton and Puffer fish extract.
Mice were divided into 9 groups, 6 mice in each group, as following
Group I: Negative control.
Group II: Positive Control.
Group III: Animals given CCl4 (1 ml/kg dissolved in olive oil) twice a week for 6 weeks.
Group IV: Mice treated for 7 consecutive days with low dose of Chiton extract (10 mg/kg).
Group V: Animals treated for 7 consecutive days with low dose of Chiton extract (10 mg/kg) then intoxicated with CCl4 as in Group III.
In this work the following studies were used:
• Chemical studies for Chiton extract.
• Biochemical studies for Chiton and Puffer fish extract.
• Histological and Histochemical studies for Chiton and Puffer fish extract.
Mice were divided into 9 groups, 6 mice in each group, as following
Group I: Negative control.
Group II: Positive Control.
Group III: Animals given CCl4 (1 ml/kg dissolved in olive oil) twice a week for 6 weeks.
Group IV: Mice treated for 7 consecutive days with low dose of Chiton extract (10 mg/kg).
Group V: Animals treated for 7 consecutive days with low dose of Chiton extract (10 mg/kg) then intoxicated with CCl4 as in Group III.
Other data
| Title | “Protective effect of marine animal extracts on carbon tetrachloride induced hepatotoxicity in mice | Other Titles | " الدور الوقائى لمستخلصات حيوانات بحرية ضد السمية الكبدية المحدثة برابع كلوريد الكربون فى الفئران | Authors | Eman Abdel Aal Abdel Aati Khalil | Issue Date | 2018 |
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