Development of Middle East Respiratory Syndrome Coronavirus (MERS-CoV) candidate vaccine

Abstract

Middle East respiratory syndrome coronavirus (MERS-CoV) disease is a viral respiratory illness to human continues to be a threat to public health. At the end of 2018 a total of 2229 laboratory confirmed human infection cases of MERS including 791 associated deaths in 27 countries (were reported globally with case fatality rate 35.5%. This study was conducted at Center of Scientific Excellence for Influenza Viruses, Water Pollution Research Department, National Research Centre to increase awareness of newly emerging MERS- CoV and drew an epidemiological map of the virus in Egypt and develop an effective vaccine against circulating virus