Studying the relationship between Dipeptidyl peptidase-4 enzyme level, Tumor necrosis factor alpha enzyme level, and insulin resistance in type 1 Diabetes Mellitus patients

Mahmoud Nabil Abdou Abdel Salam;

Abstract


Type 1 diabetes mellitus (T1DM) is an inflammatory disease of the pancreatic islets that results in absolute insulin deficiency and the consecutive hyperglycemia due to immune-mediated beta cell destruction Although β cell death is the pathophysiological core of T1DM, recent data suggest that the disease associated metabolic disturbances represent a common feature of autoimmunity and insulin resistance (IR) caused by adipocyte derived pro-inflammatory factors, chronic activation of innate immune system, and low-grade inflammation


Other data

Title Studying the relationship between Dipeptidyl peptidase-4 enzyme level, Tumor necrosis factor alpha enzyme level, and insulin resistance in type 1 Diabetes Mellitus patients
Other Titles دراسة العلاقة بين مستوي إنزيم دابيتيدايل بيتيتدير 4 وتيومر نيكروزيز فاكتور الفا و نسبة المقاومة للإنسولين في مرضي السكري من النوع الثاني
Authors Mahmoud Nabil Abdou Abdel Salam
Issue Date 2018

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