EVALUATION OF SERUM NITRIC OXIDE LEVELS IN CASES OF SEPTIC ABORTION
Amgad AL-Said Moustafa Abou-Gamrah;
Abstract
Nitric oxide research is now riding on •a crest of enthusiasm. Nitric oxide was Science's "molecule of the year" in
1992. Aspects of nitric oxide research enter into almost all areas of biology and medicine. Perhaps it is the first of a generation of "signaling gases" acting by flipping cellular redox switches rather than on specific receptors. Others may be carbon monoxide and superoxide anion. (Anggard, 1994)
Nitric oxide is an unusual messenger. It is a small molecule composed of one atom each of nitrogen and oxygen. Nitric oxide is an uncharged molecule with an unpaired electron. These characteristics of nitric oxide make it an ideal messenger molecule: Uncharged, nitric oxide can diffuse freely across membranes. With an unpaired electron, it is called a radical molecule, which is highly reactive (having a half-life of 2-30 seconds). (Lowenstein, 1994)
Nitric oxide is synthesized from the amino acid L-arginine via a family of enzymes termed nitric oxide synthases (NOS). Named for the cell type where they were frrst discovered ,there are now three known isoforms.Neuronal (nNOS,NOS1),inducible (iNOS,NOS2) and endothelial (ecNOS,NOS3)-each encoded by different genes.(Johnson & Billiar, 1998)
1992. Aspects of nitric oxide research enter into almost all areas of biology and medicine. Perhaps it is the first of a generation of "signaling gases" acting by flipping cellular redox switches rather than on specific receptors. Others may be carbon monoxide and superoxide anion. (Anggard, 1994)
Nitric oxide is an unusual messenger. It is a small molecule composed of one atom each of nitrogen and oxygen. Nitric oxide is an uncharged molecule with an unpaired electron. These characteristics of nitric oxide make it an ideal messenger molecule: Uncharged, nitric oxide can diffuse freely across membranes. With an unpaired electron, it is called a radical molecule, which is highly reactive (having a half-life of 2-30 seconds). (Lowenstein, 1994)
Nitric oxide is synthesized from the amino acid L-arginine via a family of enzymes termed nitric oxide synthases (NOS). Named for the cell type where they were frrst discovered ,there are now three known isoforms.Neuronal (nNOS,NOS1),inducible (iNOS,NOS2) and endothelial (ecNOS,NOS3)-each encoded by different genes.(Johnson & Billiar, 1998)
Other data
| Title | EVALUATION OF SERUM NITRIC OXIDE LEVELS IN CASES OF SEPTIC ABORTION | Other Titles | تقييم مقدار اوكسيد النيتريك فى الدم لحالات الاجهاض العفن | Authors | Amgad AL-Said Moustafa Abou-Gamrah | Issue Date | 2000 |
Recommend this item
Similar Items from Core Recommender Database
Items in Ain Shams Scholar are protected by copyright, with all rights reserved, unless otherwise indicated.