Neutrophil Lymphocyte Ratio and Platelet Lymphocyte Ratio as Diagnostic and Prognostic Markers for Hepatitis C Virus – Related Hepatocellular Carcinoma in Egyptian Patients

Abstract

The aim of the current study was to evaluate the role of inflammatory markers Neutrophil lymphocyte ratio and Platelet lymphocyte ratio (NLR & PLR) as biomarkers for diagnosis of HCV related HCC. Also to evaluate their role as early prognostic markers before and after different therapeutic interventions of HCC. One hundred and fourteen consecutive patients with HCC seen in the outpatient clinic of HCC Unit, Tropical Medicine Department, Ain Shams University Hospitals, in the period from January 2015 to March 2018, were enrolled into a database that was approved by the Institutional Review Board. This study was conformed to the standards of the Declaration of Helsinki and current ethical guidelines and was approved by the Research and Ethics Committee of Ain Shams University, Cairo, Egypt in accordance with local research governance requirements