Probiotics for the management of Neonatal hyperbilirubinemia

Abstract

Background In recent years, the tendency to use drugs has been increasing in the treatment of neonatal jaundice. Several drugs have been used since then, but the effect of probiotics on serum bilirubin level (SBL) is not so clear. This study was conducted to evaluate the effect of probiotics on SBL and the duration of phototherapy in term neonates with hyperbilirubinemia. Objective/ the aim of the work: To evaluate and assess the therapeutic effects of the probiotic substance on neonatal jaundice. Subjects and Methods: - In this Experimental Randomized clinical trial study we studied (400) newborns with jaundice hospitalized for phototherapy in kenayate Hospital in zagazig during 5/2017 to 5/2018 - Eligible neonates were Randomly divided into two groups: 1) Intervention (n = 200) 2) control (n= 200) Both groups receive standard conventional phototherapy but the intervention group received 250mg lactobacillus powder with milk as a probiotic substance until hospital discharge. The out come variable were.