The Role of Pre-B-cell Colony- Enhancing Factor in Egyptian Children with Hemophagocytic Lymphohistiocytosis
Reda Mostafa Mohamed;
Abstract
The main symptoms of HLH include persistent fever, pancytopenia, hepatosplenomegaly, and hemophagocytosis. Because most clinical features of HLH are nonspecific, establishing a diagnosis of HLH is time-consuming.
Because of this delayed recognition, the mortality of HLH was once as high as 95%. Currently, clinicians are seeking innovative methods for early diagnosis. However, there have been no studies to examine the role of PBEF in HLH.
Pre-B-cell colony-enhancing factor (PBEF) is an inflammatory cytokine involved in several inflammatory diseases. However, its role in HLH is unknown.
So in our study we aimed to evaluate the role of pre-B-cell colony enhancing factor (PBEF) as a diagnostic and prognostic marker in patients with HLH.
Because of this delayed recognition, the mortality of HLH was once as high as 95%. Currently, clinicians are seeking innovative methods for early diagnosis. However, there have been no studies to examine the role of PBEF in HLH.
Pre-B-cell colony-enhancing factor (PBEF) is an inflammatory cytokine involved in several inflammatory diseases. However, its role in HLH is unknown.
So in our study we aimed to evaluate the role of pre-B-cell colony enhancing factor (PBEF) as a diagnostic and prognostic marker in patients with HLH.
Other data
| Title | The Role of Pre-B-cell Colony- Enhancing Factor in Egyptian Children with Hemophagocytic Lymphohistiocytosis | Other Titles | دراسة دور عامل خلية البري بى المحفزة فى الأطفال المصريين المصابيين بداء البلعمة | Authors | Reda Mostafa Mohamed | Issue Date | 2018 |
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