Study the Effect of Aloe Vera Plant on Rats Infected by Liver Inflammatory

Abstract

The present study was carried out to investigate the protective role of Aloe Vera gel plant extract on carbon tetrachloride CCl4 induced changes in liver enzymes of albino rats. Aloe Vera is a medicinal plant belonging to the family –Liliaceae, which has a wide range of therapeutic applications such as wound healing, diabetes, burns, for easing intestinal, curing ulcers and arthritic swellings. Sixty-four male Albino rats weighing about 130±5 g was taken and divided into eight groups, each with eight rats. The first group is the control (-) and fed on normal diet for 6 weeks. The second group received subcutaneous injection with CCL4 in paraffin oil (50% v/v 2 ml/kg) twice per week for 2 weeks to induce chronic damage in the liver tissue and fed on normal diet (control +). The third, fourth and fifth groups were injected with CCL4 in paraffin oil twice per week for 2 weeks then fed on 0.3, 0.6 and 0.9ml Aloe Vera suspension gel (50 mg/mL), respectively by epi-gastric tube for remnant 4 weeks (injection groups). The sixth, seventh and eighth groups fed first on normal diet plus 0.3, 0.6 and 0.9ml Aloe Vera suspension gel, respectively by epi-gastric tube for first 4 weeks then they were injected with CCL4 in paraffin oil twice per week for remnant 2 weeks with continued fed on the same concentrations of Aloe Vera suspension gel (protected groups)