(Sofosbuvir/ledipasvir in treatment of HCV infected Egyptian patients with decompensated liver cirrhosis Child Pugh class (B

Abstract

Treatment of HCV infected patients with child class B is challenging due to their liability to pass to decompensated child C class and to be complicated with ascites, varices and other signs of liver cell failure (Lisa M.et al, 2015). Patients with decompensated cirrhosis, no HCC and a MELD score <18-20 infected with HCV genotype 1, 4, 5 or 6 should be treated with sofosbuvir and ledipasvir for 12 weeks with ribavirin (EASL, 2016).