Assessment of Serum Visfatin Level in Beta Thalassemia Patients

Amr Hany Mohamed Amin;

Abstract


Abstract

Background: Thalassemias are monogenetic hematologic disorders which are caused by faulty synthesis of one or more of the Hb chains which leads to imbalance in globin chains resulting in hemolysis and impaired erythropoiesis and chronic inflammatory condition. Visfatin is a pro-inflammatory adipocytokine which is mostly expressed in visceral adipose tissue and its testing may help in assessment of severity of the disease. Aim of the work: This study aims at measuring serum visfatin level in Beta thalassemia patients and its possible correlation to disease severity (Major and Intermedia). Patients and methods: Forty-one patients diagnosed as β-thalassemia (major, intermedia) and twenty age and sex-matched healthy individuals as the control group were tested for serum visfatin levels by enzyme-linked immunosorbent assay.-


Other data

Title Assessment of Serum Visfatin Level in Beta Thalassemia Patients
Other Titles تقييم مستوى السيرم فيسفاتين في مرضى انيميا البحر الأبيض المتوسط
Authors Amr Hany Mohamed Amin
Issue Date 2019

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